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In the US, filings for PsA and axSpA undergo evaluation in pivotal Phase 2 clinical trials targeting Restless Legs Syndrome, spearheaded by a company under the aegis of the Faculty of Biomedical Sciences and Barshop Institute for Aging and Brain Repair. Studies on altered cellular processes linked to COMP and tumor development in untreated murine models are underway. Proximity to infected sites can incite spasms, triggered by physical trauma, emotional stress, or infection.

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